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Conscious sedation for patients undergoing enteroclysis: Comparing the safety and patient-reported effectiveness of two protocols.

Maglinte DD, Applegate KE, Rajesh A, Jennings SG, Ford JM, Savabi MS, Lappas JC

Department of Radiology, Indiana University Medical Center, 550 N, University Boulevard, University Hospital Room 0279, Indianapolis, IN 46202-5253, United States.

OBJECTIVE: To compare the safety and patient-reported effectiveness of two regimens for conscious sedation during enteroclysis. MATERIALS AND METHODS: We surveyed two groups of outpatients and retrospectively reviewed procedure records for conscious sedation and complications. Patients were divided into Group One (received sedative/amnesic diazepam), and Group Two, (received amnesic/sedative, midazolam and analgesic fentanyl). RESULTS: All enteroclyses were successfully completed; there were no hospital admissions due to complications. In Group One (n=106), mean dose of diazepam was 12.7mg. 25% had oxygen desaturation (n=25), and post-procedure vomiting without aspiration (n=1). 56% of outpatients completed phone surveys, and 68% recalled procedural discomfort. In Group Two (n=45), mean doses were 3.9mg midazolam and 108mcg fentanyl. 31% had desaturation (n=13), and post-procedure vomiting without aspiration (n=1). 87% had only a vague recall of the procedure or of any discomfort. CONCLUSION: A combination of amnesic and fentanyl prevented the recall of discomfort of nasoenteric intubation and infusion in most patients who had enteroclysis compared to diazepam. Most of the patients would undergo the procedure again, if needed.

Published 31 March 2008 in Eur J Radiol.
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